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Electrochemical dopamine biosensor using over-oxidized polypyrrole with assistance of graphene

Abstract : This paper described a disposable overoxidized polypyrrole/graphene/gold (OPPy/GE/Au) microelectrode by two-step electrooxidation at a three-electrode-integrated electrochemical sensor, and its application for selective determination of dopamine (DA) without the interference of ascorbic acid (AA). Compared with the bare Au electrode, OPPy/GE/Au electrode exhibits much stronger electroactivity for DA, as well as intense electrostatic inhibition towards the oxidation of AA at the same time. Such a compatible with mass production and low-cost fabrication of on-chip DA sensor presented a sensitivity of 1.1 μA/μM with a correlation coefficient of 0.99. These properties make the prepared biosensor suitable for the analysis of trace detection of DA in most clinical preparations with a high sensitivity
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https://hal-uphf.archives-ouvertes.fr/hal-03585830
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Submitted on : Wednesday, February 23, 2022 - 2:16:34 PM
Last modification on : Wednesday, March 23, 2022 - 3:51:34 PM

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Jian Jun Zhang, Jia Zhou, Yuhua Yu, Jianfeng Chen, Wei-Jiang Xu. Electrochemical dopamine biosensor using over-oxidized polypyrrole with assistance of graphene. 2016 13th IEEE International Conference on Solid-State and Integrated Circuit Technology (ICSICT), Oct 2016, Hangzhou, China. pp.671-673, ⟨10.1109/ICSICT.2016.7999007⟩. ⟨hal-03585830⟩

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