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Caractérisation ultrasonore de milieux biologiques en suspension : application aux hématies

Abstract : This work deals the characterization of erythrocyte suspensions through the analysis of the attenuation and the velocity in the frequency range from 30 to 75 MHz. Among biological media, blood has been choosen because of the easiness of the modifications of its composition and physical and chemical properties. So that, the influence of these modifications on the elastic wave propagation can be studied. Absorption in blood results from two processes : one which is macromolecular and the other one which is corpuscular. Our main interest is in the corpuscular part because of the existence of theoretical models in which correlations with some mechanical properties of the media are established. Our experimental results are analyzed according to the frequency, the erythrocyte membrane state and the Mean Corpuscular Haemoglobin Concentration. From the theoretical model describing the elastic wave propagation in a suspension of viscous particles of small size compared to the ultrasonic wavelength, two parameters are deduced from our experimental results : the adiabatic compressibility and the thermal expansion coefficient. Both of these coefficients are related to the deformability of the erythrocyte which influences blood circulation.
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  • HAL Id : tel-03441733, version 1

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Malika Toubal. Caractérisation ultrasonore de milieux biologiques en suspension : application aux hématies. Electronique. Université de Valenciennes et du Hainaut-Cambrésis, 1996. Français. ⟨NNT : 1996VALE0038⟩. ⟨tel-03441733⟩

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